Bioss Inc.'s AFAP Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed. The AFAP Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated was generated using AFAP1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells